Unzip the portable folder to a location outside of C:\Program Files or C:\Users. Windows UAC tends to interfere with portable apps. Use D:\Torrents\ or C:\PortableApps\.
Recommended source: PortableApps.com (official repository) – they host a repackaged, clean version of uTorrent 2.2.1. utorrent 2.2.1 portable
Do not download from random “portable app” forums without scanning with VirusTotal. Unzip the portable folder to a location outside
There are no "Pro" upgrade buttons. There are no display banners at the bottom. There is no background process eating your GPU for Bitcoin. It is pure P2P file transfer code. Do not download from random “portable app” forums